Erythema nodosum may be a condition that causes painful red bumps beneath the skin on a human shins. Sometimes the bumps also have an effect on the ankles, knees, thighs, and forearms.
The condition is one in all the foremost common types of a rare inflammatory problem known as panniculitis that affects subcutaneous fat beneath the skin.
A majority of erythema nodosum (EN) cases occur in people between the ages of 20 and 45 years old. Women are five times more likely than men to develop EN.
The condition is usually relatively harmless, but it can be a sign of an underlying infection, other inflammatory conditions, or an abnormal response to an allergen or medication.